When sending an email to a company to enquire whether that company is hiring for a given position, you probably want to avoid referring to the company as “you guys.” Really. I don’t think my response to this is overreaction to some kind of assumed verbal sexism (email appears to have been written by a woman). Even if you knew knew from personal experience that every employee of this company has a penis (though if you did know that for a fact, you probably wouldn’t want to apply to that company for other reasons), I’d suggest avoiding that phrase and cranking up the professionalism just a smidgen.
My assvice for the day, take it or leave it. You’re very welcome.